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Our Story

Our research network was established by a multidisciplinary group of hypertension experts dedicated to revolutionizing the understanding and management of high blood pressure. This team encompasses basic, clinical, and epidemiological research experts, addressing all stages of life and sex differences. Recognizing the limitations of traditional approaches, they aim to break down barriers and create a framework for precision medicine tailored to individuals.

As this innovative network grows, it provides a supportive platform for emerging hypertension specialists, fostering collaboration and knowledge. Together, we are advancing the future of hypertension research and making a meaningful impact on lives with each significant breakthrough.

LEADERS

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Research Network Director

Cardiovascular Health Across the Lifespan Program

Research Institute of the McGill University Health Centre

Dr. Stella Daskalopoulou

As a hypertension expert. Her research focuses on the identification of early markers of vascular impairment and maintenance of vascular health. Her objective is to integrate biomedical technology into an innovative cardiovascular research program aimed at unraveling the arteriosclerosis and atherosclerotic process and identifying early markers of severity and progression of vascular disease, as well as treatment efficacy. Her research program aims to improve upon the current paradigm of screening, investigating, monitoring, and assessing treatment of patients with vascular risk factors and/or established atherosclerotic disease through the assessment of: a) vascular function (e.g. arterial stiffness and hemodynamics), b) imaging (ultrasound and image analysis), c) blood markers (e.g. established and novel biomarkers, microRNAs), and d) the integration of cutting edge technology. Her view in research follows a mode "from microscope-through stethoscope-to telescope" allowing her to perform translational, patient-centered research.

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Leader, Early Development and Pediatrics

Child Health and Human Development Program

Research Institute of the McGill University Health Centre​

Dr. Gabriel Altit

Dr. Altit has built a translational research program in neonatal hemodynamics. As a clinician-scientist (FRQS Junior 1) at the RI-MUHC, he founded NeoCardioLab (www.neocardiolab.com), an internationally recognized platform offering educational resources, a website, and a mobile app, used daily by the global TnECHO community. His research, supported by the American Thoracic Society, the Pediatric Research Foundation, CIHR, the Grand défi Pierre Lavoie, and the Fondation Pour Enfants Seulement, focuses on neonatal cardiovascular physiology, cardiac POCUS, and advanced imaging. In 2020, he launched and currently directs McGill’s fellowship program in neonatal hemodynamics, the only Royal College–accredited program of its kind in Quebec. Dr. Altit is an Associate Professor in the Department of Pediatrics at McGill University. He serves on the Fetus and Newborn Committee of the Canadian Paediatric Society, co-authors several national position statements, and acts as an expert advisor to INESSS on neonatal hyperbilirubinemia.

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Leader, Behavioral Research and People with Lived and Living Experiences

Brain Repair and Integrative Neuroscience Program

Research Institute of the McGill University Health Centre

Dr. Susan Bartlett

Her research focuses on behavioural factors that affect health outcomes. Dr. Barlett studies how behaviour change (e.g., diet, exercise, smoking, taking medications regularly) and emotional wellbeing (stress, depression, anxiety) can help people with inflammatory arthritis and other chronic conditions feel and function better. She also evaluates ways to make medical care more patient-centred by collaborating with patient research partners, developing better patient reported outcome measures, and improving doctor-patient communication.

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Leader, Hypertensive Disorders of Pregnancy

Cardiovascular Health Across the Lifespan Program

Research Institute of the McGill University Health Centre

Dr. Mariane Bertagnolli​

Dr. Mariane Bertagnolli is an Assistant Professor in the School of Physical and Occupational Therapy at McGill University and a scientist at the Research Institute of the McGill University Health Centre (RI-MUHC), where she co-leads the Cardiovascular Health Across the Lifespan (CHAL) Program. Her research focuses on hypertensive disorders of pregnancy, particularly pre-eclampsia, and their impact on maternal and fetal vascular health. Using a translational approach that combines murine models and clinical samples, her lab investigates mechanisms of angiogenesis and explores therapeutic strategies such as exercise rehabilitation to improve outcomes for women and their children. 

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Leader, Multi-omics analyses

Respiratory Diseases Program

Research Institute of the McGill University Health Centre

Dr. Jung Ding

His research focuses on studying cell dynamics in various biological processes in many diseases (e.g., developmental disorder, pulmonary diseases, cancers). Decoding cell dynamics is essential for understanding the pathogenesis of diseases and finding novel therapeutics. The existence of enormous heterogeneity in those diseases makes it challenging to decipher the unknown.

The advancing single-cell technologies that profile individual cell states provide unprecedented opportunities to tackle this problem, which could drive biological discoveries and medical innovations in various fields (such as developmental and cancer biology). However, the single-cell data presents numerous new challenges in developing computational models that bridge the biomedical data and potential discoveries.

Dr. Ding's primary research is to develop machine learning approaches (particularly probabilistic graphical models) to jointly analyze, model, and visualize single-cell (and/or bulk) omics data (preferably longitudinal or spatial). Such computational models will be used to help us obtain deeper understanding of the cell dynamics in different biological systems, which will eventually benefit the public health with machine-learning driven new diagnostic and therapeutic strategies.

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Leader, Database Integration

Respiratory Diseases Program

Research Institute of the McGill University Health Centre

Khalifa University

Dr. Gregory Fonseca 

​Inflammation is central to many diseases. It is a signalling process transmitted by dozens of signalling molecules in many combinations. Our lab focuses on understanding the types of inflammation that lead to disease. We use machine learning models on next-generation sequencing datasets to predict patterns associated with cytokine activation and use these to deconvolute the inflammatory response.

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Leader, Implementation

Cardiovascular Disease Across the Lifespan Program

Research Institute of the McGill University Health Centre

 Sainte-Justine  University Health Centre

Dr. Isabelle Malhamé

The overarching aim of her research program is to improve maternal health by reducing pregnancy-related severe morbidity, including from cardiovascular and thromboembolic complications. Her program focuses on the following research themes: epidemiology and risk prediction; innovation in the diagnosis and management of high-risk conditions; and quality improvement and patient safety.

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Leader, Mentoring

Cardiovascular Health Across the Lifespan Program

Research Institute of the McGill University Health Centre

​​Dr. Augusto Montezano

Dr Montezano is an active member of the hypertension scientific community, not only as a researcher but also as an advocate for mentoring and training of all researchers. He is the Social Media Editor of Hypertension, from the American Heart Association and chair of the Early Career Researchers Network (EACARE) at the Research Institute of the McGill University Health Centre. He has been advocating for Early Career Researchers at the executive and mentoring committees of the American Heart Association Council on Hypertension and the International Society of Hypertension. During his time as chair of Mentorship and Training committees in international societies, Dr Montezano has helped to create a Capacity Building Network for ECRs and participated in a podcast discussing mentorship with his international peers. In this network, he will prepare our ECRs and help to create opportunities for mentorship programs and professional growth, both locally and internationally, to empower ECRs and their career progress.

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Leader, Sex and Gender Differences

Cardiovascular Disease Across the Lifespan Program

​Research Institute of the McGill University Health Centre

Dr. Louise Pilote

Dr. Louise Pilote is a distinguished Professor of Medicine at McGill University, holding a James McGill Chair. She is the Deputy Director of the Research Institute of the McGill University Health Centre and co-founder of the Canadian Organization for Sex and Gender Sciences. Dr. Pilote is a sex and gender scientist who developed a gender measure to assess the impact of gender on cardiovascular outcomes. Dr. Pilote is internationally recognized for her expertise in sex and gender science, particularly in cardiovascular research. She has pioneered comparative effectiveness studies of cardiovascular drugs and devices, focusing on sex differences and women’s vascular health across the lifespan, and has developed methodologies to assess gender's impact on health outcomes.

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Leader, Equity, Diversity and Inclusion

Cardiovascular Health Across the Lifespan Program

Dr. Vivian Ugochinyere Ukah

Dr. Ugochinyere Vivian Ukah is an Assistant Professor in the Division of Clinical Epidemiology and Division of Experimental Medicine, in the Department of Medicine, McGill University. Her research focuses on the short- and long-term outcomes of pregnancy complications, and development, and validation of prediction models in maternal and perinatal health and examining racial disparities in perinatal outcomes. Dr Ukah holds a master’s degree in public health (Health services research) from the University of Sheffield, England and a PhD in Reproductive and Developmental Sciences from the University of British Columbia, Canada. She completed her postdoctoral fellowship at the Department of Epidemiology, Biostatistics, and Occupational Health at McGill University. Prior to joining McGill as a Professor, Dr Ukah worked as an Assistant Research Investigator in the Pregnancy & Child Research Centre, at Health Partners Institute, Minnesota, USA.

Members

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Dr. Sara Ahmed

BRAiN Program, RI-MUHC

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Dr. James Brophy

CHAL Program. RI-MUHC

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Dr. Richard Brown

CHHD Program, RI-MUHC

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Dr. David Buckeridge

MEDIC Program, RI-MUHC

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Dr. Deborah Da Costa

CHHD Program, RI-MUHC

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Dr. Natalie Dayan

CHAL Program, RI-MUHC

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Dr. Robert James Doonan

CHAL Program, RI-MUHC

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Dr. Jamie Engert

CHAL Program, RI-MUHC

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Dr. Alan Forster

SIS Program, RI-MUHC

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Dr. Isabel Fortier

CHHD Program, RI-MUHC

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Dr. Matthias Friedrich

CHAL Program, RI-MUHC

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Dr. Isabelle Gagnon

CCHD Program, RI-MUHC

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Dr. Nadia Giannetti

CHAL Program, RI-MUHC

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Dr. Iulia Iatan

CHAL Program, RI-MUHC

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Dr. Irah King

RESP Program, RI-MUHC

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Dr. Stephane Laporte

MEDIC Program, RI-MUHC

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Dr. Judy Luu

CHAL, RI-MUHC

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Dr. Loydie Jerome-Majewska

CHHD Program, RI-MUHC

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Dr. Jacek Majewski

CHHD Program, RI-MUHC

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Dr. Angeliki Makri

CHHD Program, RI-MUHC

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Dr. Thomas Mavrakanas

CHAL Program, RI-MUHC

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Dr. Nancy Mayo

BRAiN Program, RI-MUHC

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Dr. Tina Montreuil

CHHD Program, RI-MUHC

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Dr. Keith Murai

BRAin Program, RI-MUHC

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Dr. Meranda Nakhla

CHHD Program, RI-MUHC

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Dr. Romina Pace

MEDIC Program, RI-MUHC

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Dr. Ioannis Ragoussis

CHHD Program, RI-MUHC

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Dr. Sonia Semenic

CHHD Program, RI-MUHC

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Dr. Abhinav Sharma

CHAL Program, RI-MUHC

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Dr. Robert Sladek

MEDIC Program, RI-MUHC

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Dr. George Thanassoulis

CHAL Program, RI-MUHC

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Dr. Jean Francois Trempe

BRAiN Program, RI-MUHC

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Dr. Michael Tsoukas

MEDIC Program, RI-MUHC

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Dr. Rhian Touyz

CHAL Program, RI-MUHC

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Dr. Togas Tulandi

CHHD Program, RI-MUHC

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Dr. Mathew Ades

Lady Davis Institute

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Dr. Simon Bacon

Concordia University

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Dr. Andreea Gorgos

McGill University  

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Dr. Mehmet Gumus

McGill University

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Dr. Eva Kehayia

Lady Davis Institute

Administrative Staff and Research Managers

Our dedicated admin staff and research managers work tirelessly to ensure smooth operations and drive innovative projects. With a focus on collaboration and efficiency, they are committed to supporting our mission and enhancing the overall experience for all members. Together, they play a crucial role in our success and growth.

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Dr. Helena Papacostas Quintanilla

Research Network Program Manager

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Ms. Maria Matossian

Research Network Project Manager

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Dr. Mohsen Damavandi

CHAL Program Manager

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Ms. Guenievre Grodin

CHAL Program Assistant

Our Collaborators and Funding Agencies

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